![AffiAB® Anti-HE4 Antibody [JF62-09]](/web/image/product.product/74596/image_1024/%5BAFG-HB-1806%5D%20AffiAB%C2%AE%20Anti-HE4%20Antibody%20%5BJF62-09%5D%20?unique=a48b62f)
AffiAB® Anti-HE4 Antibody [JF62-09]
HE4 (whey acidic protein (WAP) -type four-disulfide core-2, WFDC2) is a small secretory protein that may influence sperm maturation. HE4 gene expression is high in pulmonary epithelial cells and in some ovarian cancers. HE4 protein has a WAP motif that contains eight cysteines forming four disulfide bonds at the core of the protein. The WAP motif functions as a protease inhibitor in many of the family members that contain them.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q14508 Human; SwissProt: Q9DAU7 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JF62-09
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human HE4 aa 78-114 / 124.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: Use at an assay dependent concentration.
Molecular Weight
23 kDa
Subcellular location
Secreted.
Positive control
SW480 cell lysate, SKOV-3 cell lysate, HepG2 cell lysate, SKOV-3, SW480, mouse lung tissue.