![AffiAB® Anti-HAPLN1 Antibody [SY02-17]](/web/image/product.product/74576/image_1024/%5BAFG-HB-1785%5D%20AffiAB%C2%AE%20Anti-HAPLN1%20Antibody%20%5BSY02-17%5D%20?unique=a48b62f)
AffiAB® Anti-HAPLN1 Antibody [SY02-17]
The human cartilage link protein, also designated HAPLN1, is a member of the hyaluronan and proteoglycan link protein (HAPLN) family of proteins. This family contains 4 proteins with approximately 50% homology. The human cartilage link protein strengthens tissue architecture by using hyaluronic acid to stabilize the aggregates of proteoglycan monomers inside the extracellular cartilage matrix. It is widely expressed in most tissue types except brain tissue where, much like the other human cartilage link protein genes, it is weakly expressed. The HAPLN and the brain-specific CSPG genes, as well as other members of the link module superfamily, appear to have a common ancestral gene origin.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P10915 Human; SwissProt: Q9QUP5 Mouse; SwissProt: P03994 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SY02-17
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P
Predicted species reactivity
Rat, Zebrafish
Immunogen
Synthetic peptide withinl Human HAPLN1 aa 305-354 / 354.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:50-1:100; IF-Tissue: 1:50-1:100; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 40 kDa
Subcellular location
Secreted.
Positive control
BT-20 cell lysate, HUVEC cell lysate, SW480 cell lysate, HUVEC, SW480, BT-20, human tonsil tissue, human liver tissue, human spleen tissue, mouse spleen tissue.