AffiAB® Anti-HADHSC Antibody [D10-E7]
Hydroxyacyl-Coenzyme A dehydrogenase also known as HADH is an enzyme which in humans is encoded by the HADH gene. This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. A deficiency is associated with 3-hydroxyacyl-coenzyme A dehydrogenase deficiency.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q16836 Human; SwissProt: Q61425 Mouse; SwissProt: Q6DI22 Zebrafish
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
D10-E7
KO/KD
N/A
Species reactivity
Human, Mouse, Zebrafish
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human HADHSC aa 265-314 / 314.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:200-1:500; IHC-P: 1:400
Molecular Weight
Predicted band size: 34 kDa
Subcellular location
Mitochondrion matrix
Positive control
293T, human liver, mouse liver, zebrafish, HepG2, Human kidney tissue, Human colon cancer.