![AffiAB® Anti-GST3 Antibody [JB40-79]](/web/image/product.product/74562/image_1024/%5BAFG-HB-1771%5D%20AffiAB%C2%AE%20Anti-GST3%20Antibody%20%5BJB40-79%5D%20?unique=a48b62f)
AffiAB® Anti-GST3 Antibody [JB40-79]
Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P09211 Human; SwissProt: P19157 Mouse; SwissProt: P04906 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JB40-79
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Cell, IF-Tissue
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human GST3aa 70-210 / 210.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 23 kDa
Subcellular location
Cytoplasm, Mitochondrion, Nucleus.
Positive control
A549 cell lysate, mouse liver tissue lysate, A431, A549, LOVO, rat epididymis tissue, human liver tissue, human placenta tissue, mouse fallopian tube tissue, human lung tissue, human lung squamous carcinoma tissue .