AffiAB® Anti-GNB2 Antibody [JE47-16]
Guanine nucleotide-binding protein G (I) /G (S) /G (T) subunit beta-2 is a protein that in humans is encoded by the GNB2 gene. Heterotrimeric guanine nucleotide-binding proteins (G proteins) , which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P62879 Human; SwissProt: P62880 Mouse; SwissProt: P54313 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE47-16
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human GNB2 aa 1-130 / 340.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500-1:1, 000
; IHC-P:1:50-1:200
; FC:1:50-1:100
Molecular Weight
Predicted band size: 37 kDa
Subcellular location
Perinuclear region.
Positive control
MCF-7 cell lysate, SK-Br-3 cell lysate, SH-SY5Y cell lysate, rat kidney tissue, mouse brain tissue, MCF-7.