AffiAB® Anti-GABRA2 Antibody
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P47869 Human; SwissProt: P26048 Mouse; SwissProt: P23576 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human GABRA2 aa 29-200 / 451 (Extracellular) .
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; FC: 1:500-1:1, 000
Molecular Weight
51 kDa
Subcellular location
Postsynaptic cell membrane, Cell membrane, Cytoplasmic vesicle membrane, Dendrite.
Positive control
Rat brain tissue lysates, mouse brain tissue lysate, mouse cerebellum tissue lysate, human brain tissue lysate, Hela.