AffiAB® Anti-Flightless 1 Antibody
May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity) . May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q13045 Human; SwissProt: Q9JJ28 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human Flightless 1 aa 1100-1269 / 1269.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IHC-P: 1:100-1:500
Molecular Weight
145 kDa
Subcellular location
Cytoskeleton, centrosome, nucleus, focal adhesion.
Positive control
Mouse lung tissue lysate, MCF-7 cell lysate, rat testis tissue, human tonsil tissue, human lung tissue.