![AffiAB® Anti-FKBP52 Antibody [JG96-30]](/web/image/product.product/74303/image_1024/%5BAFG-HB-1484%5D%20AffiAB%C2%AE%20Anti-FKBP52%20Antibody%20%5BJG96-30%5D%20?unique=a48b62f)
AffiAB® Anti-FKBP52 Antibody [JG96-30]
Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q02790 Human; SwissProt: P30416 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG96-30
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human FKBP52 aa 1-132 / 459.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 52 kDa
Subcellular location
Cytoplasm. Cytoskeleton. Microtubule. Mitochondrion. Nucleus.
Positive control
SK-Br-3 cell lysate, 293 cell lysate, 293T, MCF-7, human prostate cancer tissue, human esophagus tissue, mouse brain tissue.