![AffiAB® Anti-FAM62B Antibody [C4-D0]](/web/image/product.product/74245/image_1024/%5BAFG-HB-1421%5D%20AffiAB%C2%AE%20Anti-FAM62B%20Antibody%20%5BC4-D0%5D%20?unique=d31c23b)
AffiAB® Anti-FAM62B Antibody [C4-D0]
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) .
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: A0FGR8 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
C4-D0
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human FAM62B aa 300-550.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein G affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IHC-P: 1:50-1:200
Molecular Weight
102 kDa
Subcellular location
Cell membrane, Endoplasmic reticulum, Membrane.
Positive control
Siha cell lysate, THP-1 cell lysate, human colon carcinoma tissue.