![AffiAB® Anti-FADS1 Antibody [JE55-63]](/web/image/product.product/74235/image_1024/%5BAFG-HB-1410%5D%20AffiAB%C2%AE%20Anti-FADS1%20Antibody%20%5BJE55-63%5D%20?unique=a48b62f)
AffiAB® Anti-FADS1 Antibody [JE55-63]
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O60427 Human; SwissProt: Q920L1 Mouse; SwissProt: Q920R3 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE55-63
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within N-terminal Human FADS1.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:100; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 52 kDa.
Subcellular location
Mitochondrion, Endoplasmic reticulum membrane.
Positive control
Rat liver tissue lysate, mouse liver tissue lysate, mouse brain tissue lysate, rat lung tissue lysate, Hela cell lysate, A549 cell lysate, Hela, PANC-1, human liver carcinoma tissue, human thyroid tissue, human colon carcinoma tissue, human breast carcinoma tissue, human stomach carcinoma tissue, human small intestine tissue, A549.