AffiAB® Anti-Factor IX Antibody
Factor IX (or Christmas factor) (EC 3.4.21.22) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes haemophilia B. It was discovered in 1952 after a young boy named Stephen Christmas was found to be lacking this exact factor, leading to haemophilia.Factor IX complex is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.The gene for factor IX is located on the X chromosome (Xq27.1-q27.2) and is therefore X-linked recessive: mutations in this gene affect males much more frequently than females.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P00740 Human; SwissProt: P16294 Mouse; SwissProt: P16296 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human Factor IX aa 20-70.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:500; IHC-P: 1:100-1:500; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 52 kDa.
Subcellular location
Secreted.
Positive control
K562 cell lysate, Siha cell lysate, rat liver tissue, human liver tissue, human placenta tissue, mouse liver tissue, SiHa.