![AffiAB® Anti-Exportin-5 Antibody [JE40-91]](/web/image/product.product/74220/image_1024/%5BAFG-HB-1395%5D%20AffiAB%C2%AE%20Anti-Exportin-5%20Antibody%20%5BJE40-91%5D%20?unique=a48b62f)
AffiAB® Anti-Exportin-5 Antibody [JE40-91]
The karyopherin-related nuclear transport factor Exportin 5, also known as Exp5, preferentially recognizes and transports RNAs containing minihelix motifs, structural cis-acting export elements that comprise a double-stranded stem (14 nucleotides) with a base-paired 5' end and a 3-8-nucleotide protruding 3' end. Exportin 5 also mediates protein transport between the nuclear and cytoplasmic compartment. Exportin 5 belongs to a large family of karyopherins and stimulates nuclear export of dsRNA binding proteins eEF1A and tRNA.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9HAV4 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE40-91
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC, IF-Cell, IF-Tissue
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Exportin-5 aa 1-240 / 1, 204.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IHC-P: 1:100-1:400; FC: 1:50-1:100; IF-Cell: 1:100; IF-Tissue: 1:100
Molecular Weight
136 kDa
Subcellular location
Cytoplasm. Nucleus.
Positive control
293, rat epididymis tissue, human lung cancer tissue, human thyroid gland tissue, human breast tissue, mouse testis tissue, K562.