AffiAB® Anti-EVI1 Antibody
Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q03112 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human Evi-1 aa 1-200.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
MAPK signaling pathway
Recommended dilutions
WB: 1:500-1:1, 000
Molecular Weight
107/138 kDa
Subcellular location
Cytoplasm, Nucleus.
Positive control
293 cell lysates, A431 cell lysates.