![AffiAB® Anti-ERAS Antibody [D10-B9]](/web/image/product.product/74179/image_1024/%5BAFG-HB-1350%5D%20AffiAB%C2%AE%20Anti-ERAS%20Antibody%20%5BD10-B9%5D%20?unique=315d7a9)
AffiAB® Anti-ERAS Antibody [D10-B9]
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity) . Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP) .
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q7Z444 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
D10-B9
KO/KD
N/A
Species reactivity
Human
Tested applications
IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human ERAS aa 1-233 / 233.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
IF-Cell:1:50; IHC-P:1:200-1:500
Molecular Weight
Predicted band size: 25 kDa
Subcellular location
Cell membrane.
Positive control
NCCIT, human liver carcinoma tissue, human breast carcinoma tissue.