![AffiAB® Anti-Eftud2 Antibody [1-D10-A1]](/web/image/product.product/74117/image_1024/%5BAFG-HB-1282%5D%20AffiAB%C2%AE%20Anti-Eftud2%20Antibody%20%5B1-D10-A1%5D%20?unique=315d7a9)
AffiAB® Anti-Eftud2 Antibody [1-D10-A1]
Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: O08810 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
1-D10-A1
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within mouse Eftud2 aa 1-50 / 972.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 109 kDa
Subcellular location
Nucleus.
Positive control
Jurkat cell lysate, NIH/3T3 cell lysate, SH-SY-5Y, SW480, mouse colon tissue, human lung cancer tissue, mouse prostate tissue, human colon cancer tissue, MCF-7.