AffiAB® Anti-Dynamin 3 Antibody
Dynamin-3 is a protein that in humans is encoded by the DNM3 gene. The protein encoded by this gene is a member of the dynamin family which possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding. DNM3 is upregulated in Sézary's syndrome.Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity) .
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9UQ16 Human; SwissProt: Q8BZ98 Mouse; SwissProt: Q08877 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human Dynamin 3 aa 820-869.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Neuroscience
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:200
Molecular Weight
97 kDa
Subcellular location
Cytoplasm, Cytoskeleton, Microtubule.
Positive control
Rat brain tissue lysate, NIH/3T3 cell lysate, human brain tissue lysates, mouse brain tissue.