AffiAB® Anti-DUSP5 Antibody
Dual specificity protein phosphatase 5 is encoded by the DUSP5 gene, which is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q16690 Human; SwissProt: Q1HL35 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human DUSP5 aa 71-120 / 384.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
MAPK signaling pathway
Recommended dilutions
WB: 1:500; IF-Cell: 1:50
Molecular Weight
Predicted band size: 42kDa
Subcellular location
Nucleus, Cytoplasm
Positive control
K562, Hela