![AffiAB® Anti-DPY30 Antibody [1-6]](/web/image/product.product/74067/image_1024/%5BAFG-HB-1229%5D%20AffiAB%C2%AE%20Anti-DPY30%20Antibody%20%5B1-6%5D%20?unique=315d7a9)
AffiAB® Anti-DPY30 Antibody [1-6]
As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q9C005 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
1-6
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within mouse DPY30 aa 1-99 / 99.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500
Molecular Weight
11kDa
Subcellular location
Golgi apparatus, Nucleus
Positive control
F9