AffiAB® Anti-DOPEY2 Antibody
Dopey-2, a 2, 298 amino acid protein, belongs to the dopey family, that is overexpressed in lymphoblasts from Down syndrome patients and Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon. Multiple isoforms of Dopey-2 exist due to alternative splicing events. Dopey-2 is thought to play a role in protein trafficking between early endosomes and the late.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9Y3R5 Human; SwissProt: Q3UHQ6 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human DOPEY2 aa 1025-1074 / 2, 298.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IHC-P: 1:50-1:200; IF-Cell: 1:50-1:500; FC: 1:50-1:100
Molecular Weight
Predicted band size: 258kDa
Subcellular location
Early endosome membrane, Golgi apparatus membrane.
Positive control
Mouse heart, human heart, Siha, N2A, Mouse brain,