AffiAB® Anti-DAZL Antibody [JA10-36]

DAZL (deleted in azoospermia-like) , an RNA-binding protein that effects spermatogenesis, is an autosomal homolog of the Y chromosome DAZ (deleted in azoospermia) . The gene encoding human DAZL maps to chromosome locus 3p24. DAZL, like other members of The DAZ family members are included in germ cells in both male and female gonads. A Thr 54-to-Ala mutation within the RNA-recognition domain of DAZL proteins contributes to spermatogenic failure. Infertility in DAZL knockout catisatalities are unable to complete the first meiotic prophase in the first wave of spermatogenesis.