![AffiAB® Anti-Hu CD56 PerCP-Cy5.5 [LT56]](/web/image/product.product/83838/image_1024/%5BAFG-EXB-2339%5D%20AffiAB%C2%AE%20Anti-Hu%20CD56%20PerCP-Cy5.5%20%5BLT56%5D?unique=d31c23b)
Overview
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
Specificity:
The mouse monoclonal antibody LT56 recognizes an extracellular epitope of CD56 (NCAM), a transmembrane glycoprotein expressed ubiquitously in the nervous system and found also on T cells and NK cells.
Antigen
CD56
Clone
LT56
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
Cell line KG1a
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PerCP-Cy5.5
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide