![AffiAB® Anti-Hu CD305 PerCP-Cy5.5 [NKTA255]](/web/image/product.product/83835/image_1024/%5BAFG-EXB-2336%5D%20AffiAB%C2%AE%20Anti-Hu%20CD305%20PerCP-Cy5.5%20%5BNKTA255%5D?unique=d31c23b)
Overview
CD305, also known as LAIR1 (leukocyte-associated Ig-like receptor 1), is an inhibitory receptor found on many types of peripheral blood cells. It serves to suppress cell cytotoxicity, activation, proliferation, and differentiation regarding autoantigens via its two intracellular ITIM sites. CD305 belongs to the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family of proteins. It reacts with collagen ligands.
Specificity:
The mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.
Antigen
CD305
Clone
NKTA255
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Activated NK cells and CD3- thymocytes
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PerCP-Cy5.5
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide