![AffiAB® Anti-Hu CD94 PE-Cy7 [HP-3D9]](/web/image/product.product/83721/image_1024/%5BAFG-EXB-2222%5D%20AffiAB%C2%AE%20Anti-Hu%20CD94%20PE-Cy7%20%5BHP-3D9%5D?unique=d31c23b)
Overview
CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process.
Specificity:
The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells.
Antigen
CD94
Clone
HP-3D9
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
Cultured human NK cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE-Cy7
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide