Overview
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa) . Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Specificity:
The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.
Antigen
Ig Kappa Light Chain
Clone
A8B5
Species Reactivity
Human
Negative Species
Rabbit, Hamster, Sheep, Guinea pig, Goat
Isotype
Mouse IgG1
Immunogen
N/A
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
Pacific Blue
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide