![AffiAB® Anti-Hu CD326 Alexa Fluor 647 [323/A3]](/web/image/product.product/83360/image_1024/%5BAFG-EXB-1861%5D%20AffiAB%C2%AE%20Anti-Hu%20CD326%20Alexa%20Fluor%20647%20%5B323-A3%5D?unique=d31c23b)
Overview
CD326 / EpCAM (also known as ESA, EGP40, EGP-2, KSA1/4, CO17-1A, GA733-2, MOC31, Ber-EP4) is a 40 kDa transmembrane glycoprotein serving as adhesion molecule in the basolateral membranes in a variety of epithelial cells. CD326 mediates calcium-independent homotypic cell-cell adhesions. CD326 over-expression has been detected in many epithelial tumours and is often associated with bad prognosis. It has been used for diagnostics of (pre-) malignancies at early stages.
Specificity:
The mouse monoclonal antibody 323/A3 recognizes an extracellular epitope of CD326 / EpCAM, a marker of epithelial lineages, that is over-expressed in many carcinomas.
Antigen
CD326
Clone
323/A3
Species Reactivity
Human
Negative Species
Rat
Isotype
Mouse IgG1
Immunogen
Human breast cancer MCF-7 cells
Application
FC (QC tested), WB, ICC
Regulatory status
RUO
Concentration
N/A
Format
Alexa Fluor® 647
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide