![AffiAB® Anti-Hu beta2-Microglobulin Alexa Fluor 647 [B2M-01]](/web/image/product.product/83345/image_1024/%5BAFG-EXB-1846%5D%20AffiAB%C2%AE%20Anti-Hu%20beta2-Microglobulin%20Alexa%20Fluor%20647%20%5BB2M-01%5D?unique=24195c2)
Overview
Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
Specificity:
The mouse monoclonal antibody B2M-01 reacts with beta2-microglobulin (beta2M; extracellular antigen), associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
Antigen
beta2-Microglobulin
Clone
B2M-01
Species Reactivity
Human
Negative Species
Rabbit, Dog, Mouse, Cow, Chicken
Isotype
Mouse IgG2a
Immunogen
Purified human beta2-microglobulin
Application
FC (QC tested), WB, ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Alexa Fluor® 647
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide