Overview
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence.
Specificity:
The mouse monoclonal antibody IVA26 recognizes an extracellular epitope on MHC class I (alpha + beta2m chains) expressed in various animals.
Antigen
MHC Class I (α+β2m chains)
Clone
IVA26
Species Reactivity
Mouse, Pig, Cow, Human, Rabbit, Sheep, Coturnix japonica
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
bovine lymphocytes
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.5 mg/ml
Format
Alexa Fluor® 488
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide