![AffiAB® Anti-Bov CD9 Alexa Fluor 488 [IVA50]](/web/image/product.product/83286/image_1024/%5BAFG-EXB-1787%5D%20AffiAB%C2%AE%20Anti-Bov%20CD9%20Alexa%20Fluor%20488%20%5BIVA50%5D?unique=d31c23b)
Overview
CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
Specificity:
The antibody IVA50 reacts with an extracellular epitope of CD9 antigen (bovine), a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes. This antibody crossreacts with CD9 on human platelets.
Antigen
CD9
Clone
IVA50
Species Reactivity
Human, Cow
Negative Species
N/A
Isotype
Mouse IgG2
Immunogen
Bovine thrombocytes.
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.5 mg/ml
Format
Alexa Fluor® 488
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide