![AffiAB® Anti-Cytokeratin 19 Alexa Fluor 488 [A53-B/A2]](/web/image/product.product/83261/image_1024/%5BAFG-EXB-1762%5D%20AffiAB%C2%AE%20Anti-Cytokeratin%2019%20Alexa%20Fluor%20488%20%5BA53-B-A2%5D?unique=0daa593)
Overview
Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Specificity:
The mouse monoclonal antibody A53-B/A2 recognizes the rod domain of cytokeratin 19 (40 kDa), an intracellular antigen constituting intermmediate cytoskeleton filaments. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.
Antigen
Cytokeratin 19
Clone
A53-B/A2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
MCF-7 human breast adenocarcinoma cell line
Application
FC (QC tested), WB, ICC
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
Alexa Fluor® 488
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide