![AffiAB® Anti-Cytokeratin 18 Alexa Fluor 488 [C-04]](/web/image/product.product/83259/image_1024/%5BAFG-EXB-1760%5D%20AffiAB%C2%AE%20Anti-Cytokeratin%2018%20Alexa%20Fluor%20488%20%5BC-04%5D?unique=0daa593)
Overview
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins) .
Specificity:
The antibody C-04 reacts with cytokeratin 18 (45 kDa intracellular antigen), a member of intermediate filaments subfamily represented in epithelial tissues.
Antigen
Cytokeratin 18
Clone
C-04
Species Reactivity
Mammalian
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Cytoskeleton preparation of epidermal carcinoma cell line A431.
Application
FC (QC tested), WB, ICC
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
Alexa Fluor® 488
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide