![AffiAB® Anti-Rt PLSCR1 Ascites [13A6 [TEC-23]]](/web/image/product.product/83252/image_1024/%5BAFG-EXB-1753%5D%20AffiAB%C2%AE%20Anti-Rt%20PLSCR1%20Ascites%20%5B13A6%20%5BTEC-23%5D%5D?unique=0daa593)
Overview
PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.
Specificity:
The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.
Antigen
PLSCR1
Clone
13A6 [TEC-23]
Species Reactivity
Rat
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
Pooled lipid raft fraction isolated from RBL-2H3 cells
Application
IP, WB, ICC, FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
Ascites
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Stabilized with 15mM sodium azide.