![AffiAB® Anti-Hu CD226 PE [11A8]](/web/image/product.product/83236/image_1024/%5BAFG-EXB-1737%5D%20AffiAB%C2%AE%20Anti-Hu%20CD226%20PE%20%5B11A8%5D?unique=d31c23b)
Overview
CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.
Specificity:
The mouse monoclonal antibody 11A8 recognizes an extracellular epitope within CD226 transmembrane glycoprotein.
Antigen
CD226
Clone
11A8
Species Reactivity
Non-human primates, Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
N/A
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide