![AffiAB® Anti-Hu CD173 PE [MEM-195]](/web/image/product.product/83232/image_1024/%5BAFG-EXB-1733%5D%20AffiAB%C2%AE%20Anti-Hu%20CD173%20PE%20%5BMEM-195%5D?unique=d31c23b)
Overview
CD173 (blood group antigen H2) is a fucosylated saccharide (Fuc-alpha-1-2-Gal-beta-1-4-GlcNAc-beta) generated by beta-D-galactoside 2-alpha-L-fucosyltransferase (FUT1) . CD173 belongs to markers of early hematopoiesis; it is expressed mainly on CD34-positive hematopoietic progenitor cells. CD173 is a precursor structure of CD174 (Lewis Y) and is also structurally related to CD15 (Lewis X) . On endothelial cells CD173 and CD174 are concentrated on pseudopodial extensions responsible for initial contacts between endothelial cells.
Specificity:
The antibody MEM-195 reacts with CD173 (H2), an extracellular saccharide antigen expressed mainly during early hematopoiesis; it is also expressed on endothelial cells.
Antigen
CD173
Clone
MEM-195
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgM
Immunogen
Human thrombocytes
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide