AffiAB® Anti-Hu CD319 PE [162]

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CAT# AFG-EXB-1731
Size: 100 Tests

$ 281.00 281.0 USD $ 281.00

$ 281.00

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Overview

CD319 is a homophilic type I transmembrane protein with two intracellular immunoreceptor tyrosine-based switch motives (ITSMs) . It is expressed by cytotoxic T cells, activated B cells, NK cells, and mature dendritic cells. CD319 triggers NK cell-mediated cytotoxicity. Ligation of CD319 can induce proliferation, cell adhesion, cytokine secretion, and cytotoxicity of T cells and NK cells.

Specificity:

The mouse monoclonal antibody 162 recognizes an extracellular epitope of human CD319, a transmembrane glycoprotein expressed by cytotoxic T cells, activated B cells, NK cells, and mature dendritic cells.

Antigen

CD319

Clone

162

Species Reactivity

Human

Negative Species

N/A

Isotype

Mouse IgG2b

Immunogen

Recombinant extracellular domain of human CD319 (204 aa) fused with Fc part of human IgG1

Application

FC (QC tested)

Regulatory status

RUO

Concentration

N/A

Format

Storage / Stability

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Storage Buffer

Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide