AffiAB® Anti-Hu C3aR PE [HC3aRZ8]

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CAT# AFG-EXB-1725
Size: 0.1 mg

281.00 281.0 USD 281.00

281.00

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Overview

C3aR is a 7TM transmembrane protein associated with G proteins, and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils, mast cells, basophils, eosinophils, dendritic cells, monocytes, and macrophages. Upon detection of its ligand, the activated C3aR signaling cascade results in degranulation, superoxide production, and chemotaxis.


Specificity:

The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR, a transmembrane chemotactic receptor for C3a anaphylatoxin.

Antigen

C3aR

Clone

HC3aRZ8

Species Reactivity

Human

Negative Species

N/A

Isotype

Mouse IgG2b

Immunogen

Human C3aR transfectants

Application

FC (QC tested)

Regulatory status

RUO

Concentration

N/A

Format

PE

Storage / Stability

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Storage Buffer

Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide