![AffiAB® Anti-Hu CD307a PE [E3]](/web/image/product.product/83209/image_1024/%5BAFG-EXB-1710%5D%20AffiAB%C2%AE%20Anti-Hu%20CD307a%20PE%20%5BE3%5D?unique=d31c23b)
Overview
CD307a is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITAM motifs in its cytoplasmic domain. CD307a is expressed mainly on the surface of mature B-cells, and is down-regulated in germinal center B-cells. Expression of CD307a is higher in patients with autoimmune diseases, compared with healthy controls.
Specificity:
The mouse monoclonal antibody E3 recognizes an extracellular epitope of CD307a, a transmembrane glycoprotein expressed predominantly on the surface of mature B cells.
Antigen
CD307a
Clone
E3
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
DNA-immunization followed by a boost with the CD307a transfected cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide