![AffiAB® Anti-Hu CD307c PE [H5]](/web/image/product.product/83207/image_1024/%5BAFG-EXB-1708%5D%20AffiAB%C2%AE%20Anti-Hu%20CD307c%20PE%20%5BH5%5D?unique=d31c23b)
Overview
CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.
Specificity:
The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.
Antigen
CD307c
Clone
H5
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b kappa
Immunogen
DNA-immunization followed by a boost with CD307c transfected cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide