![AffiAB® Anti-Hu CD307d PE [A1]](/web/image/product.product/83206/image_1024/%5BAFG-EXB-1707%5D%20AffiAB%C2%AE%20Anti-Hu%20CD307d%20PE%20%5BA1%5D?unique=d31c23b)
Overview
CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG) . Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.
Specificity:
The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.
Antigen
CD307d
Clone
A1
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
DNA-immunization followed by a boost with CD307d-transfected cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide