![AffiAB® Anti-Hu CD62E PE [HAE-1f]](/web/image/product.product/83197/image_1024/%5BAFG-EXB-1698%5D%20AffiAB%C2%AE%20Anti-Hu%20CD62E%20PE%20%5BHAE-1f%5D?unique=d31c23b)
Overview
CD62E (E-selectin) is a type I transmembrane glycoprotein of 97 - 115 kDa. It recognizes carbohydrate ligands on various molecules, and promotes leukocyte extravasation by mediating leukocyte rolling on activated endothelia during inflammation. CD62E is expressed above all in inflammated endothelium, but it can also be found on resting endothelium in certain organs, such as skin, or placenta.
Specificity:
The mouse monoclonal HAE-1f recognizes an extracellular epitope of CD62E, a transmembrane glycoprotein expressed on activated endothelial cells, as well as in skin, placenta, and bone marrow endothelium.
Antigen
CD62E
Clone
HAE-1f
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
TNF-activated HUVEC and human CD40 cDNA-transfected cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide