AffiAB® Anti-Lysozyme PE [LZ598-10G9]

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CAT# AFG-EXB-1677
Size: 100 Tests

281.00 281.0 USD 281.00

281.00

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Overview

Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils) . It damages bacterial cell walls by hydrolysis of 1, 4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium.


Specificity:

The mouse monoclonal antibody LZ598-10G9 recognizes lysozyme, an approximately 17 kDa antibacterial enzyme, which is being used as a marker for the lineage diagnosis of acute leukemias (intracellular antigen) .

Antigen

Lysozyme

Clone

LZ598-10G9

Species Reactivity

Human

Negative Species

N/A

Isotype

Mouse IgG1

Immunogen

human lysozyme

Application

FC (QC tested)

Regulatory status

RUO

Concentration

0.1 mg/ml

Format

PE

Storage / Stability

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Storage Buffer

Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide