![AffiAB® Anti-Acidic Cytokeratins PE [AE1]](/web/image/product.product/83147/image_1024/%5BAFG-EXB-1648%5D%20AffiAB%C2%AE%20Anti-Acidic%20Cytokeratins%20PE%20%5BAE1%5D?unique=0daa593)
Overview
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. CThey are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Specificity:
Mouse monoclonal antibody AE1 recognizes acidic type cytokeratins (intracellular antigens), namely K10, 14, 15, 16, 19 (40-56 kDa) . This antibody stains well the basal layer of epidermis and most epithelia.
Antigen
Acidic Cytokeratins
Clone
AE1
Species Reactivity
Rabbit, Cat, Rat, Mouse, Human, Dog, Chicken, Non-human primates
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Human epidermal keratins
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide