![AffiAB® Anti-Ms NK1.1 PE [PK136]](/web/image/product.product/83141/image_1024/%5BAFG-EXB-1642%5D%20AffiAB%C2%AE%20Anti-Ms%20NK1.1%20PE%20%5BPK136%5D?unique=0daa593)
Overview
NK1.1 / CD161bc (also known as NKRP1, Ly55c, or Ly59) is a cell surface antigen expressed on NK cells and NK-T cells of certain mouse strains, which is being used for identification or antibody-mediated depletion of these cells in the respective strains. This antigen participates in NK cell activation, including production of interferon gamma, and release of cytotoxic granules.
Specificity:
The mouse monoclonal antibody PK136 recognizes an extracellular epitope of NK1.1 antigen (NK cell marker) expressed by some mouse strains (e.g. C57BL/6, NZB, CE, C58, Ma/My), whereas other strains (e.g. BALB/c, AKR, CBA, C3H) do not express this antigen. This antibody detects a conformational epitope on Nkrp1c and Nkrp1b gene products.
Antigen
NK1.1
Clone
PK136
Species Reactivity
Mouse
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
NK1-positive murine splenic and bone marrow cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.5 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide