![AffiAB® Anti-DDIT4L PE [DDIT-03]](/web/image/product.product/83117/image_1024/%5BAFG-EXB-1618%5D%20AffiAB%C2%AE%20Anti-DDIT4L%20PE%20%5BDDIT-03%5D?unique=0daa593)
Overview
DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
Specificity:
The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.
Antigen
DDIT4L
Clone
DDIT-03
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide