![AffiAB® Anti-OPAL1 PE [OPAL1-01]](/web/image/product.product/83101/image_1024/%5BAFG-EXB-1602%5D%20AffiAB%C2%AE%20Anti-OPAL1%20PE%20%5BOPAL1-01%5D?unique=0daa593)
Overview
OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.
Specificity:
The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
Antigen
OPAL1
Clone
OPAL1-01
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
Recombinant fragment of human OPAL1 (amino acids 152-342)
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide