![AffiAB® Anti-Hu CD36 PE [CB38]](/web/image/product.product/83061/image_1024/%5BAFG-EXB-1562%5D%20AffiAB%C2%AE%20Anti-Hu%20CD36%20PE%20%5BCB38%5D?unique=d31c23b)
Overview
CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.
Specificity:
The mouse monoclonal antibody CB38 (NL07) recognizes an extracellular epitope of CD36 (GPIIIb), a 85-113 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes.
Antigen
CD36
Clone
CB38
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgM kappa
Immunogen
living human myeloid cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide