![AffiAB® Anti-Hu CD229 PE [HLy9.25]](/web/image/product.product/83048/image_1024/%5BAFG-EXB-1549%5D%20AffiAB%C2%AE%20Anti-Hu%20CD229%20PE%20%5BHLy9.25%5D?unique=d31c23b)
Overview
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
Specificity:
The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
Antigen
CD229
Clone
HLy9.25
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
CD299-transfected 300.19 pre-B cell line
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide