![AffiAB® Anti-Ms CD90.2 PE [1aG4/C5]](/web/image/product.product/82990/image_1024/%5BAFG-EXB-1491%5D%20AffiAB%C2%AE%20Anti-Ms%20CD90.2%20PE%20%5B1aG4-C5%5D?unique=d31c23b)
Overview
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. In the mouse, CD90 is expressed mainly on thymocytes and peripheral T lymphocytes. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
Specificity:
The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse Thy-1 (CD90) ; it does not cross-react with Thy-1.1 alloantigen. Thy-1 is an 18-35 kDa cell surface GPI anchored glycoprotein (immunoglobulin superfamily) ; in mouse it is abundant on thymocytes and peripheral T lymphocytes.
Antigen
CD90.2
Clone
1aG4/C5
Species Reactivity
Mouse
Negative Species
Rat, Human
Isotype
Mouse IgG3
Immunogen
thymocytes from C3H/Di mice (Thy-1.2 positive)
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide