![AffiAB® Anti-Hu CD132 PE [TUGh4]](/web/image/product.product/82904/image_1024/%5BAFG-EXB-1405%5D%20AffiAB%C2%AE%20Anti-Hu%20CD132%20PE%20%5BTUGh4%5D?unique=d31c23b)
Overview
CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID) . CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.
Specificity:
The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.
Antigen
CD132
Clone
TUGh4
Species Reactivity
Human, Dog
Negative Species
N/A
Isotype
Rat IgG2b kappa
Immunogen
Human CD132-transfected cell line
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide