![AffiAB® Anti-Ms CD16/CD32 PE [93]](/web/image/product.product/82865/image_1024/%5BAFG-EXB-1366%5D%20AffiAB%C2%AE%20Anti-Ms%20CD16-CD32%20PE%20%5B93%5D?unique=d31c23b)
Overview
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.
Specificity:
The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
Antigen
CD16/CD32
Clone
93
Species Reactivity
Mouse
Negative Species
N/A
Isotype
Rat IgG2a lambda
Immunogen
Murine pre-B cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.5 mg/ml
Format
PE
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide