Overview
CD318 (CUB domain containing protein 1) is a complement domains-containing transmembrane glycoprotein, which takes part in early hematopoiesis. It is expressed on CD34+CD133+ bone marrow cells, keratinocytes, and in human colorectal and breast cancers. It is being used as a marker of mesenchymal stem-like cells, neural progenitor cells, and also as an independent marker for the diagnosis of myeloid leukemias.
Specificity:
The mouse monoclonal antibody CUB1 recognizes an extracellular epitope of CD318, a type I transmembrane protein involved in early hematopoiesis.
Antigen
CD318
Clone
CUB1
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
NIH-3T3/CD318 cells
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
FITC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide